体細胞からIPS細胞そして臼歯再生

2015-12-1


コロンビア大学のチームが体細胞から作成したIPS細胞で、人間の臼歯の作成に成功したとの記事がありました。
私も10年後にはメタルのインプラントではなく、IPS作成した本物の歯を植え付けられる状況に夢を馳せます。
以下本文


Human molar scaffolding
Columbia University Medical Center
Dr. Jeremy Mao has unveiled a technique that directs the body’s stem cells into a scaffolding that will aid in the regeneration of a new tooth.
The loss of a tooth is a minor deformity and a major pain. Although dental implants are available, the healing process can take months on end, and implants that fail to align with the ever-growing jawbone tend to fall out. If only adult teeth could be regenerated, right?
According to a study published in the latest Journal of Dental Research, a new tissue regeneration technique may allow people to simply regrow a new set of pearly whites.
Dr. Jeremy Mao, the Edward V. Zegarelli Professor of Dental Medicine at Columbia University Medical Center, has unveiled a growth factor-infused, three-dimensional scaffold with the potential to regenerate an anatomically correct tooth in just nine weeks from implantation. By using a procedure developed in the university’s Tissue Engineering and Regenerative Medicine Laboratory, Dr. Mao can direct the body’s own stem cells toward the scaffold, which is made of natural materials. Once the stem cells have colonized the scaffold, a tooth can grow in the socket and then merge with the surrounding tissue.
Dr. Mao’s technique not only eliminates the need to grow teeth in a Petri dish, but it is the first to achieve regeneration of anatomically correct teeth by using the body’s own resources. Factor in the faster recovery time and the comparatively natural process of regrowth (as opposed to implantation), and you have a massively appealing dental treatment.
Columbia University has already filed patent applications in regard to the technology and is seeking associates to aid in its commercialization. In the meantime, Dr. Mao is considering the best approach for applying his technique to cost-effective clinical therapies.
[Columbia University Medical Center]

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